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Guareschi-Thorpe condensation : ウィキペディア英語版
2-Pyridone

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2-Pyridone is an organic compound with the formula . This colourless crystalline solid is used in peptide synthesis. It is well known to form hydrogen bonded structures somewhat related to the base-pairing mechanism found in RNA and DNA. It is also a classic case of a molecule that exists as tautomers.
== Structure ==
The most prominent feature of 2-pyridone is the amide group; a nitrogen with a hydrogen bound to it and a keto group next to it. In peptides, amino acids are linked by this pattern, a feature responsible for some remarkable physical and chemical properties. In this and similar molecules, the hydrogen bound to the nitrogen is suitable to form strong hydrogen bonds to other nitrogen- and oxygen-containing species.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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